Tag Archives: gwas

When fold-enrichment is more informative than p-values: #TopAnat analysis of autism genes from GWAS

In a recent post on this blog we saw how to analyze results from a breast cancer GWAS. In that case, we did not have very strong expectations of tissue-specificity for the genes; it was more of an exploratory analysis. … Continue reading

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#TopAnat where are genes significant in a breast cancer GWAS expressed?

Genome Wide Association Studies (GWAS) report many significant SNPs, which may be associated to many genes. How can we make sense of them? One way is to compute enrichment of the resulting gene list for properties of interest. For example … Continue reading

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